thank you for your question. Published results generally show that handgun fatalities or handgun's changing someones behavioral style are in the 10-25% range IIRC. There are so many variables, one person might fall down after being shot in the hand with a 22 LR, while another might keep trying to kill you after being shot multiple times with a 45ACP. The fatality thing is more quantifiable, and I have not seen the study in a while but based on a very large number of shootings the difference in lethality between a 45 and a 9mm is not that far apart. There are a myriad of factors that influence this not just the bore size. For instance some people choose a 45ACP, but cannot shoot it that well and might make a hit with it, but not a lethal hit. It is also conceivable that the .1 inch difference in bore size at handgun speeds is not that significant provided both bullets penetrate as deeply.