I've seen how Woodleigh's 286 gn RN and PP worked on about 60 of our buffalo, as well as a good number of big pigs. Most of these were more or less close - some close enough and coming in hard enough to focus my attention pretty sharply - and I have had no reason to think I needed a 320 grainer. Both 286 gn versions would punch right on through a buff, or at least end up under the skin on the far side, but I'd give the edge to the RN for anything smaller as it seemed to open better than the PP at 9.3x62 and 9.3x74R velocities.