I have a fairly old, tang safety, Ruger M77 in .30-06. I've owned it since the '70s.

I have 2 all-purpose loads for it, that my particular rifle likes...

165gr Sierra GameKing BTHP
Win brass and WLR primer
48.0grs of IMR 4064
2700 fps range out of a 22" barrel.
5-shot groups are under 0.75 moa
This load is devastating on Muleys and White-Tails.

180gr Nosler Partition
Win brass and WLR primer
54.5grs of IMR 4350
2700fps from my 22" barrel
5 shot groups around 0.6 moa
I've taken Elk sized game with this, if the shot range is reasonable. The recovered Partitions lose the whole front part of the bullet. They work every time.