I figure there's a good probability I've killed as much running game with a rifle as anybody here and more than most. Lets just say that while my hunting/shooting experience may not be geographically wide comparatively, it runs pretty deep. In addition to the deer and cottontails already mentioned, there have been countless snowshoe hares, gray squirrels, foxes, woodchucks and a few coyotes killed while on the run with rifles over the years. I won't mention the winged game brought to bag while on the fly as most would call me a liar anyway. Of course none of those would require the level of skill of your mulies or jack rabbits but I think I know what works on the game we have here under the conditions we hunt it as well as anybody.