406 - it's not a Lapua Scenar bullet he's using, it's the Berger VLD. Different critter. I've had great results on mule deer with the Berger VLD's but I don't know how comfortable I'd be with them for ticked-off grizzly...
In 2009 we were hunting the sagebrush flats for mule deer, me with a .25-06 & Bergers, my buddy with a .270 Win. Didn't find many bucks down low so we went up into the mountains and hiked in. Shortly we found grizzly sow & cub tracks... I didn't feel real good about my rifle & bullets about then. We got out with two mule deer. Boned them out and packed 'em on our backs, but with a wary eye out for the grizz.
Promised myself after that trip that if I hunted that area again, it would be with a bigger rifle and heavier Nosler Partitions.
