With Lapua brass and the 180 BT I'd definitely feel comfortable running more powder. JB ran 49gn TAC in one article and 50 in another with Fed brass. I've run 49 in Fed brass. Got a little sticky in 100deg temps and a REAL hot barrel/chamber.

At 2700+ and with the accuracy you're seeing, whatever you hit will be dead. Think how many things died from 180gn bullets out of a 30-06 at ~2700fps.