If you have magic Bullets like Barnes X or Nosler Partitions then 25-06 is good enough for lower 48. Maybe anything if you are a stuntshooter.
I used a "243 equivalent" 6x222 mag (6x47) and the older 85gr xbt on axis and a scimitar horned oryx one Spring after a neck surgery. I had it in a 27" Shilen going 2900fps, ha.
