The Russian invasion of Ukraine may put at risk a network of US-linked labs in Ukraine that work with dangerous pathogens, said Robert Pope, the director of the Cooperative Threat Reduction Program, a 30-year-old Defense Department program that has helped secure the former Soviet Union’s weapons of mass destruction and redirect former bioweapons facilities and scientists toward peaceful endeavors.
The labs in Ukraine are not bioweapons facilities. The US government maintains that they are public and animal health labs operated by host countries. Although a long-running Russian disinformation campaign has painted a picture of a network of US military labs in Ukraine, Georgia, and other former Soviet republics involved in bioweapons or risky research, Pope said the labs conduct peaceful scientific research and disease surveillance. Outside experts have also said Pope’s program is not a covert bioweapons operation.
While the United States isn’t maintaining bioweapons facilities, Pope said, war could put pathogen collections in Ukraine at risk.
“I would say from every facility that we have worked with them in, we have confidence that as long as the electrical power is turned on and the people we have trained are present at the facility, the biosafety officers, that these pathogens are safe and secure to international standards,” Pope said. “Should these facilities be damaged by conflict, that could change.”
The pathogens with which the Cooperative Threat Reduction Program labs work are generally kept frozen, so they can’t replicate and become infectious. The risk the pathogens pose would increase if a building lost power and suffered damage. “If you lose the electrical power, the pathogens in the freezers warm up,” he said. “If the ventilation system is damaged, or the building itself is damaged, and these now ambient-temperature pathogens are able to escape the facility, then they can be potentially infectious in the region around the facility.”
Although Russian officials and media have misrepresented the US-supported labs in Ukraine and other former Soviet countries in disinformation campaigns, Pope doesn’t believe the Russians will deliberately aim weapons at the labs during the invasion.
“I think the Russians know enough about the kinds of pathogens that are stored in biological research laboratories that I don’t think they would deliberately target a laboratory,” Pope said. “But what I do have concerns about is that they would … be accidentally damaged during this Russian invasion.”
The invasion could also provide fodder for new disinformation narratives around the labs, Pope feared. The Russians, he said, “could potentially go to one of these facilities and fabricate something that they call evidence of nefarious activity at the facility.”
The pathogens in Ukrainian labs vary by facility, Pope said, but some can be characterized as presenting a concern in the Ukrainian environment. As an example, he cited African swine fever virus, which is highly contagious in pigs and has caused hundreds of outbreaks in Ukraine since 2012. Some labs, he said, may hold pathogen strains left over from the Soviet bioweapons program, preserved in freezers for research purposes.
“There is no place that still has any of the sort of infrastructure for researching or producing biological weapons,” Pope said. “Scientists being scientists, it wouldn’t surprise me if some of these strain collections in some of these laboratories still have pathogen strains that go all the way back to the origins of that program.”
The program is encouraging host countries to reduce the scope of their pathogen holdings to as small of a collection as necessary for legitimate scientific research, Pope said.
“What we have today and what these countries maintain are small amounts of various pathogens that by and large are things that are collected out of their environment that they need for research to be able to legitimately surveil disease and develop vaccines against,” he said.
This work, Pope said, continued in Ukraine until recently. “They have more pathogens in more places than we recommend,” he said. The program had been helping Ukrainian researchers sift through their frozen pathogen collections, with the goal of persuading the Ukrainians to preserve their genetic information of samples via sequencing before destroying the live samples.
Pope said his program had been close to an agreement with the Ukrainians on consolidating samples, but the invasion has now made that project uncertain. “All of that, obviously, has been derailed here with the recent events,” he said.
The Cooperative Threat Reduction Program, Pope said Thursday, has not had contact with biosafety staff at the labs in Ukraine since the Russian invasion. Phone lines have been jammed in Ukraine, he said, and “I don’t know what kind of contact we will have in these labs in the near future.”
Some Ukrainian labs, like the Ukrainian Ministry of Health’s Public Health Center, Pope said, are major facilities, others small. Some are new, while others date back to the Soviet-era and the country’s bioweapons program.
The US government has worked with 26 facilities in Ukraine. Before the invasion, the program provided direct material support to six Ukrainian labs. The program also provides biosafety and scientific mentorship training to Ministry of Health personnel throughout the country.
