Hodgdon data is not very good - they have lots of pressure errors for starters. The real gap with the best powders at SAAMI max pressure is often less than 100 ft/s depending on bullet. That won't get you 100y.
The .30-06 can of course be improved by increasing the pressure IF the brass you're using is designed for over-pressure use. With the right brass you could probably run it at 65K in certain guns (.308 too). Problem is, as far as I know no one makes that brass.
