I haven't met a guide yet that will pair up with someone that hunts hot.
When hunting with guides I've always started with an empty chamber. My experience (3-4 trips domestically and one to Africa) is that after a few hours, they've sized up the client's gun handling skills and are OK with going hot, at least in situations where a shot is likely.
Of course I unload when riding in a vehicle, crawling up a steep hill, rock-hopping across streams, etc.
When hunting with others I mainly worry about their muzzle control (or lack thereof). There's a reason the NRA's #1 safety rule is "Always keep the gun pointed in a safe direction."
