Great ! I have neglected the Hornady 250-gr Monoflex. Might take faster powder than H4198, but that is a great place to start.
At gunner500's comment on correcting 5-yard chrono velocity to MV: It occurs to me that a table or graph might be handy. BC vs MV. Higher BC less loss. Higher MV more loss over that first 5 yards ...
I will keep you all posted with my results. I’m thinking that big 458 should make them scoot pretty decent.