Sir Matt, Save the H4198, best for 250-350-grainers. CFE-223 is excellent with 500-grainers. Should be about perfect for the excellent 450-gr TSX too. Will review my data after domestic chores are done.
I don't have any load data for CFE223 in the 458 Win mag, but I have a lot of it
Oh yeah ... The 450-gr TSX is a great bullet if you do not have a 404-gr Shock Hammer. I still have not beaten AA-2230 and AA-2460 with either of those bullets for top speed, though there are many powders yet to be tried. Heavily compressed H4895 might do it, but that is a bit of a bother. Other powders can clean the bore and might be more temperature independent, and the ball powders do pack better, etc. Really, anymore than 2300 fps MV with 450-grainers is gravy anyway. That might be possible with CFE 223, and I hope Sir Matt will try it and report here on chronograph results ...
Here is a medium speed load with compressed H4895 and the 450-gr TSX, loaded with long COL, so seating depth is about like the Hornady RNSN above:
Compare the Alliant Varmint powder to CFE 223, both with same rifle, same day, same 500-gr RNSN at 3.480" COL, Varmint is faster with less powder too.
Ron aka "Rip" for Riflecrank Internationale Permanente NRA Life Benefactor and Beneficiary .458 Winchester Magnum, Magnanimous in Victory THE WALKING DEAD does so remind me of Democrap voters. Donkeypox.