OK, with the rarity of 3000-pound bison bulls, only 1.0 H&H unit of TBPI is required for the "Ultimate Buffalo Rifle." That will take care of about any critter up to 2500 pounds on the hoof.
Sir Jerry is onto a good load with his 450-gr TSX at 2418 fps with 83 grains of AA-2460. Ditto Sir Bob with his 450-gr TSX at 2413 fps load with 84 grains of H335. Both of those are from 24" barrels, corrected to MV by adding 11 fps to 5-yard chrono velocity, IIRC.
Previous top 450-grainer load from my Ruger No. 1 .458 WM with 24" barrel: 450-gr TSX, Hornady .458 WM brass, F-215 primer, COL 3.565", 87*F 83.0 grains AA-2230 3 shots, 5-yard Caldwell G2 chrono fps: 2493, 2495, 2492 Average = 2493 fps, so for BC = 0.369: MV = 2504 fps
First 2 shots went into one hole at 50 yards and I pulled the third shot by a half inch, or that is when my forend screw started bending and loosening. Ho hum. Fixed that.
Better not shoot any 3000-pound bison bulls past 400 yards. That is about the limit of my marksmanship on caribou anyway, with a .340 WbyMag, which is a puny cartridge compared to the .458 WM+.
Good stuff, Sir Ron,
In about a week I'll be taking off for a few days "Down East", so will miss some blog writing until I get back. Then I'll be checking in here again!
With our Federal Election tomorrow, followed by getting matters ready for the trip... well you know how that goes!