I would have zero hesitation about using the 458 on anything in North America. I believe in the “smoke ‘em if you got ‘em”. That 450 TSX at your velocity is definitely a performer. That hide exit certainly removes any doubt that bullet expanded. In my guesstimation, all bets are off to “the eat right up to the hole” once bone pieces are being flung around, regardless of bullet. I unzipped a coyote once, by a 338 Winchester 225 TSX traveling lengthwise down the spine. Coyote tenderloin was hanging 4’ high on spruce limbs behind him. Damnest hole I have ever seen.
